Acyclovir Induced Nephrotoxicity
Keywords:
acute kidney failure, acyclovir nephrotoxicity, crystal nephropathyAbstract
Acute kidney injury is a well recognized side effect of some medications, and has been well described as an unfortunate complication with the use of acyclovir. The most common presentation of this type of injury is an acute decrease in renal function that develops within 24-48 hours with rapid increase in the level of serum creatinine. The most common mechanism of this type of lesion seems to be that of a crystal nephropathy and although it is a very well known side effect, has been poorly noticed.(8) This case clearly describes the clinical manifestations of this type of nephrotoxicity.
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