Typical radiological manifestations of sarcoidosis: a review of three cases

Abstract

Introduction: Sarcoidosis is a multisystemic granulomatous disease of unknown etiology. The lungs are the primary organ involved. It is known as the great mimicker since it exhibits a variety of symptoms, mimicking other inflammatory, infectious, and neoplastic conditions such as tuberculosis and lymphoma. Objective: Present the typical radiological manifestations of pulmonary sarcoidosis
in three patients with varying pattern and severity. Clinical cases: Three Asian women, two of which complained of a history of chronic cough and ocular symptoms, the third case complaining of cutaneous lesions. All cases presented mediastinal lymphadenopathy and pulmonary infiltrates on imaging studies. Two out of the three cases showed granulomata in spleen and liver. One case had regression of lymphadenopathy, while the other two persisted with pulmonary involvement. Conclusion: Diagnosing sarcoidosis can be a challenge but combining clinical symptoms with radiological manifestations can aid in the diagnosis. Hallmark signs of this disease include the presence of mediastinal lymphadenopathy along with respiratory symptoms.